The Jaguars defeated the Raiders today, meaning they are still one game up on the Colts in the AFC South. This means next week's game Indianapolis between the Colts and Jaguars is for all the marbles. If the Jaguars win, they very likely take the division, make the playoffs, and send the Colts home for January. If the Colts win, both teams are tied atop the South, with the Colts in position to win the division if they win out.
Bottom line, Colts must win next week, or they are finished.