From ESPN's Mark Schlereth:
It's official Peyton Manning ruled out of Sunday's game
And thus ends the NFL's current, active consecutive streak of 208 regular season starts. We all knew this was coming. It's just weird to see it in print like that. This will be the first game since 1994, as a freshman at Tennessee, that Peyton Manning will not start a game. Peyton was 18-years-old the last time he didn't start a game. That's almost half his lifetime ago.
On the positive side, at least we get to see ESPN's resident ass clown Rick Reilly eat bugs and dog poop off your carpet. From Reilly back on August 30th, via Deadspin:
Peyton Manning will keep his streak alive. If you think he's going to miss a start because of a neck problem, you've been chugging paint thinner. This guy hasn't missed a start since 1994 at Tennessee. Do you know how long ago it was when Manning didn't start for the Colts? Google was two days old. Kim Kardashian was 17. Russell Crowe was skinny! If Manning doesn't start Game 1, I will come to your house and eat things that are stuck in your carpet.
Hope it tastes like I feel right now, Rick.