There are the obvious comparisons: A new general manager, a can't miss quarterback prospect.
However; Grigson and Luck have a much harder task ahead of them. When Polian inherited the Colts and, dare I say, lucked into Manning, the Colts offense was already only a quarterback away. In 1994 the team added hall of famer Marshall Faulk at RB. In 95 they picked up a new QBs best friend in a good tight end, Ken Dilger. In 96, they drafted IMO one of the top 3 receivers in the history of the NFL in Harrison, and in 97 they drafted the great Tarik Glenn at LT and another good offensive lineman in Adam Meadows.
Polian and Manning came into a good situation, one that was ready to succeed.
Looking at the current team, Grigson and Luck have inherited next to nothing from the Polians. Our offensive line is built on the hope of Costanzo and Ijalana, our receivers are non-existant, and our running backs have succeeded in being one of the worst groups in the NFL for the past few seasons. Oh, and our tight end is aging, can't block, is recovering from injury, and couldn't hold onto the football last year.
While our defense was atrocious for the last 5 years, we need to focus on building the offense around Luck this off season. It's essential we shore up the O-line, we need to draft a WR with our second pick (or a TE), and we need to hope we get lucky with late round or free agent RBs. If I'm the Colt's front office, I'm putting all my effort into making sure we have some talent around Luck, and plan to build the defense later. Luck is now the future of this franchise, and most likely we aren't going to be a serious contender next year, So focus on building the offense and Luck now, and worry about the defense later (and hope the switch in scheme will pay dividends.) If this means trading Freeney for another pick to help shore up the offense and to free up cap space, then by all means, do it.