EAST RUTHERFORD, NJ - SEPTEMBER 05: Quarterback Eli Manning #10 of the New York Giants looks on after getting knocked down against the Dallas Cowboys during the 2012 NFL season opener at MetLife Stadium on September 5, 2012 in East Rutherford, New Jersey. (Photo by Al Bello/Getty Images)
Matt Grecco: Giants 28-24
Nick Ragsdale: Giants 24-17
MY PICK: Giants 31-17
New York must win this game. If they don't, I will seriously reconsider their chances of making the playoffs.
Don't forget to check out SBNation.com's picks as well.