Phil B announces that WR Austin Collie and SS Bob Sanders have been ruled out of Sunday's contest against the Chargers. Additionally, S Chip Vaughn has been placed on injured reserve (crowded club!) and free agent S Al Aflava has been signed to fill his vacated roster spot.
It is also being reported that RB Joseph Addai will return to non-contact conditioning drills this week, but no word on his availability Sunday, though it doesn't look good as the dreaded "no timetable" clause was attached. I would assume that Addai is out until we hear he's consistently back to full practices. You don't want a RB out there playing with one good shoulder.
As far as Sanders, I'd look for him to return to practice next week and we'll see where it goes from there. Purely speculation on my part, though.