The Colts complete their opening road circuit with a trip to Nashville to take on the Tennessee Titans. They’ve had great luck against the Titans, winning 17 of their last 20 meetings. Those don’t matter now though. Jacoby Brissett will lead the offense this time in place of Andrew Luck, and the Colts defense will need to step up their performance to deliver another loss to the Titans and move forward in the division.
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